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DYRK1A Recombinant Human Protein DFS Item

DYRK1A Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3785

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Catalog No. PV3785



Description

Description

DYRK1A is a dual specificity kinase involved in cell proliferation. The gene for DYRK1A is located in the Down syndrome critical region of chromosome 21, and has been implicated in the pathogenesis of this disease.
Specifications

Specifications

NP_001387
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
113kDa
85% by SDS-PAGE
–80°C
1 Each
DYRK1A, DYRK1
DYRK1A was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β−glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 200μg/mL DYRKtide peptide substrate (RRRFRPASPLRGPPK) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinases and inhibitors
DYRK kinase family
2880nmoles of phosphate transferred to DYRKtide peptide substrate (RRRFRPASPLRGPPK) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 0.83μg/mL
GST Tag
0.16mg/mL
1859, 2100
DYRK1A Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
DYRK1A Recombinant Human Protein
Kinase assay
Baculovirus
DYRK1A Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.