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Thermo Scientific™ DyLight™ Near-IR Specialty Dyes

Label amine-containing molecules for fluorescence imaging or flow cytometry with these benzopyrillium- and cyanine-based, infrared-emitting (633 or 700 laser) NHS ester dyes.

$340.75 - $381.35


Quantity 1mg
Sufficient For 1 use to label a total of 7mg of IgG using typical conditions
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Products ${productFamilyLength}
Catalog Number Mfr. No. Description Price Quantity  
Catalog Number Mfr. No. Description Price Quantity  
PI46646 Thermo Scientific™
DyLight 675-B1 NHS Ester Each for $374.10
PI46647 Thermo Scientific™
DyLight 675-B2 NHS Ester Each for $381.35
PI46648 Thermo Scientific™
DyLight 675-B3 NHS Ester Each for $381.35
PI46649 Thermo Scientific™
DyLight 675-B4 NHS Ester Each for $381.35
PI53003 Thermo Scientific™
DyLight 679-C5 NHS Ester Each for $340.75
PI53023 Thermo Scientific™
DyLight 690- B1 Free Acid Each for $340.75
PI53026 Thermo Scientific™
DyLight 690-B2 NHS Ester Each for $381.35
PI53028 Thermo Scientific™
DyLight 700-B1 NHS Ester Each for $375.55
PI53030 Thermo Scientific™
DyLight 700-B2 NHS Ester Each for $381.35
PI53032 Thermo Scientific™
DyLight 730-B1 NHS Ester Each for $381.35
PI53033 Thermo Scientific™
DyLight 730-B2 NHS Ester Each for $381.35
PI53036 Thermo Scientific™
DyLight 730-B3 NHS Ester Each for $381.35
PI53037 Thermo Scientific™
DyLight 730-B4 NHS Ester Each for $374.10
PI53040 Thermo Scientific™
DyLight 747-B2 NHS Ester Each for $374.10
PI53041 Thermo Scientific™
DyLight 747-B3 NHS Ester Each for $381.35
PI53042 Thermo Scientific™
DyLight 747-B4 NHS Ester Each for $381.35
PI53054 Thermo Scientific™
DyLight 775-B2 NHS Ester Each for $381.35
PI53055 Thermo Scientific™
DyLight 775-B3 NHS Ester Each for $381.35
PI53064 Thermo Scientific™
DyLight 780-B1 NHS Ester Each for $381.35
PI53065 Thermo Scientific™
DyLight 780-B2 NHS Ester Each for $381.35
PI53066 Thermo Scientific™
DyLight 780-B3 NHS Ester Each for $374.10
PI53067 Thermo Scientific™
DyLight 830-B2 NHS Ester Each for $374.10
PI85150 Thermo Scientific™
DyLight 775-B4 NHS Ester Each for $343.65


Thermo Scientific™ DyLight Near Infrared Specialty Dyes offer a broad spectrum of options for labeling molecules with tissue-penetrating near infrared (NIR) fluorescence signatures.

DyLight NIR Dyes are a family of labeling agents that can be used for bright fluorescence detection in cell-based imaging or in vivo imaging applications. NIR dyes can be selected based upon their characteristic excitation and emission properties or relative hydrophilicity/hydrophobicity attributes. Dyes that contain a greater number of negatively charged sulfonates generally will have greater water solubility than dyes with fewer sulfonates. More hydrophobic dyes often provide better cell penetrating ability in vivo, while more hydrophilic dyes have less nonspecific binding potential. Each dye contains an amine-reactive NHS ester for simple modification of antibodies, proteins, peptides or other biomolecules through amide bond formation. NIR dyes are best for imaging through tissues and away from indigenous fluorescent biomolecule interference or quenching. DyLight Near Infrared Dyes represent the largest selection of fluorescent labels that are commercially available.


  • Large selection–the largest family of dyes available for NIR fluorescence applications
  • NHS ester reactive group–allows immediate labeling of antibodies, proteins, peptides and other amine-containing molecules through amide bond formation
  • Broad spectrum of water solubilities–choose from hydrophilic to hydrophobic dyes to optimize the right dye label for the best performance in a given application
  • NIR dyes avoid background interference–DyLight NIR Dyes avoid fluorescence interference or quenching effects from biomolecules present in samples
  • Excellent signal penetration through cells and tissues–DyLight NIR Dyes provide the optimal window for excitation and emission for in vivo imaging applications

Criteria to consider when choosing a DyLight NIR Specialty Dye:

  • Excitation and emission wavelengths–choose the best dye to match the excitation and emission capabilities of your instrument
  • Water solubility–choose a DyLight NIR Dye based on its relative hydrophilicity, which directly correlates to the number of negatively-charged sulfonates it has on its core structure. More hydrophilic dyes are best at maintaining water solubility of a labeled antibody and limiting the nonspecific binding of the conjugate. More hydrophobic dyes often are best at penetrating tissues and cell membranes in vivo, meaning that dyes with fewer sulfonates may work best for some applications.
  • DyLight Dye selection–the broad selection of NIR dyes allows a number of candidate dyes to be tested in a given application for optimal performance

Recommended for:

In vivo or ex vivo imaging; Tumor imaging with labeled peptides; NIR fluorescence (NIRF) imaging of labeled silica nanoparticles; NIR in vitro imaging and characterization; Determination of thermal stability; Cytotoxicity assays; Molecular imaging; UV-VIS-NIR spectroscopy; Fluorescence correlation spectroscopy; MRI applications; DNA sequencing; Primer labeling for PCR; 2-D gel electrophoresis; Flow cytometry/fluorescence-activated cell sorting (FACS); Laser scanning confocal microscopy

Description & Specifications


1 use to label a total of 7mg of IgG using typical conditions