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Alfa Aesar™ Doxorubicin hydrochloride, 10mg/mL in distilled water, sterile filtered

Manufacturer:  Alfa Aesar™ J67364XF

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Catalog No. AAJ67364XF




Doxorubicin hydrochloride, 10mg/mL in distilled water, sterile-filtered; Liquid; Alfa Aesar; 1mL; CAS: 25316-40-9

It acts as an antitumor antibiotic agent that inhibits DNA topoisomerase II and acts as a DNA intercalator that inhibits nucleic acid synthesis and induces apoptosis. It reduces intracellular tau levels. By intercalating within DNA, doxorubicin inhibits nucleic acid synthesis and induces apoptosis by inducing the accumulation of the p53 tumor suppressor protein. It is an is an inhibitor of AMPK, TERT and POLR. its fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes. It is applied as an antineoplastic.

Fully miscible in water and soluble in 50 mM in DMSO, methanol and isotonic sodium chloride (>10 mg/ml). Insoluble in chloroform, and ether.

Protect from heat. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store in freezer at -20°C.
Description & Specifications


Doxorubicin hydrochloride
10mg/mL in distilled water, sterile-filtered

Chemical Identifiers

Doxorubicin hydrochloride, 10mg/mL in distilled water, sterile-filtered

Safety and Handling

SDS & Safety Documents

GHS H Statement
May cause cancer.

GHS P Statement
Use personal protective equipment as required.
Obtain special instructions before use.
Do not handle until all safety precautions have been read and understood.
IF exposed or concerned: Get medical advice/attention.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.


RTECSNumber : QI9295900

storageNote1 : -30° to -10°C