Thermo Scientific™ Lab Vision™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody
Obtain accurate, reprucible results in western blotting experiments with Thermo Scientific™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS1402P1ABX
Obtain accurate, reprucible results in western blotting experiments with Thermo Scientific™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody.DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
Host Species: Mouse
Species Reactivity: Human. Others not known.
Epitope: Not determined
Immunogen: DNA polymerase β protein
Molecular Weight: 39kDa
Positive Control: HeLa cells, Testis
Cellular Localization: Nuclear
- Western Blotting
USA: RUO; Int'l: RUO
|DNA Polymerase, beta Ab-2|
|DNA polymerase beta protein|