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Thermo Scientific™ Lab Vision™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody


Obtain accurate, reprucible results in western blotting experiments with Thermo Scientific™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1402P1ABX

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Catalog No. MS1402P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen DNA Polymerase, beta Ab-2
Applications Western Blotting
Classification Monoclonal
Clone 61
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen DNA polymerase beta protein
Isotype IgG2a
Quantity 100µL
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary

Obtain accurate, reprucible results in western blotting experiments with Thermo Scientific™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody.

DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.

Host Species: Mouse

Clone: 61

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: DNA polymerase β protein

Molecular Weight: 39kDa

Positive Control: HeLa cells, Testis

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO