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Thermo Scientific™ Lab Vision™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody

Obtain accurate, reprucible results in western blotting experiments with Thermo Scientific™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS1402P1ABX

 View more versions of this product

Catalog No. MS1402P1ABX


 

Specifications

Description

Obtain accurate, reprucible results in western blotting experiments with Thermo Scientific™ DNA Polymerase, β Ab-2, Mouse Monoclonal Antibody.

DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.

Host Species: Mouse

Clone: 61

Isotype: IgG2a

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: DNA polymerase β protein

Molecular Weight: 39kDa

Positive Control: HeLa cells, Testis

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

DNA Polymerase, beta Ab-2
Monoclonal
1mg/mL
Human
Murine
IgG2a
RUO
Primary
Human
Western Blot
61
Unlabeled
Concentrated
DNA polymerase beta protein
100μL
DNA Repair
Monoclonal