Thermo Scientific™ Lab Vision™ DNA Polymerase, β Ab-1, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ DNA Polymerase, β Ab-1, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific™ Lab Vision™ MS669P1ABX
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ DNA Polymerase, β Ab-1, Mouse Monoclonal Antibody.DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.
Host Species: Mouse
Species Reactivity: Human, Cow, Mouse, Rat, Hamster and Xenopus. Others not known.
Epitope: Not determined
Immunogen: Rat DNA polymerase β protein
Molecular Weight: 39 kDa
- Western Blotting
- Immunoprecipitation (Denatured verified)
- Effect on Polymerase Activity (Noninhibitory)
USA: RUO; Int'l: RUO
|DNA Polymerase, beta Ab-1|
|Rat DNA polymerase beta protein|