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Thermo Scientific™ Lab Vision™ DNA Polymerase, β Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ DNA Polymerase, β Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS669P1ABX

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Catalog No. MS669P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen DNA Polymerase, beta Ab-1
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 18S
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Xenopus
Format Concentrated
Host Species Mouse
Immunogen Rat DNA polymerase beta protein
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline DNA Repair
Type Primary

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ DNA Polymerase, β Ab-1, Mouse Monoclonal Antibody.

DNA polymerase Β comprises an amino-terminal 8-kDa domain and a carboxy-terminal 31-kDa domain. The N-terminal ssDNA binding domain has a deoxyribose phosphodiesterase activity while the C-terminal domain has a nucleotidyltransferase activity. Mammalian DNA polymerase Β, a DNA repair polymerase, is constitutively expressed in cultured cells, but treatment of cells with the DNA-alkylating agents such as N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) or methyl methanesulfonate up-regulates β-pol level. DNA polymerase Β fills single nucleotide gaps in DNA produced by the base excision repair pathway of mammalian cells.

Host Species: Mouse

Clone: 18S

Isotype: IgG1

Species Reactivity: Human, Cow, Mouse, Rat, Hamster and Xenopus. Others not known.

Epitope: Not determined

Immunogen: Rat DNA polymerase β protein

Molecular Weight: 39 kDa

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Denatured verified)
  • Effect on Polymerase Activity (Noninhibitory)

Note:

USA: RUO; Int'l: RUO