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DLL1 (delta-like 1) Armenian Hamster anti-Mouse, Alexa Fluor 488, Clone: HMD1-5, eBioscience™

Armenian Hamster Monoclonal Antibody

$187.05 - $448.05

Specifications

Antigen DLL1 (delta-like 1)
Clone HMD1-5
Host Species Armenian Hamster
Gene Alias DL1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016767

 
affymetrix
53-5767-80
25μg Each for $187.05

5016768

 
affymetrix
53-5767-82
100μg Each for $448.05
Description & Specifications

Specifications

Antigen DLL1 (delta-like 1)
Clone HMD1-5
Host Species Armenian Hamster
Gene Alias DL1
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The HMD1-5 monoclonal antibody reacts with mouse Delta-like 1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Delta-like 1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by γ-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Delta-like 1 is expressed by thymic stromal cells, as well as on macrophages, dendritic cells, and stromal cells in the spleen. This protein is also expressed in nonhematopoietic tissues such as the lung and brain. Delta-like 1 has been linked to B cell development and differentiation, especially marginal zone and plasma cells, regulation of splenic dendritic cells, and leukemogenesis.