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DLL1 (delta-like 1) Monoclonal Antibody (HMD1-5), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Armenian Hamster Monoclonal Antibody
Supplier: Thermo Fisher Scientific 53576782
Description
Description: The HMD1-5 monoclonal antibody reacts with mouse Delta-like 1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Delta-like 1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Delta-like 1 is expressed by thymic stromal cells, as well as on macrophages, dendritic cells, and stromal cells in the spleen. This protein is also expressed in nonhematopoietic tissues such as the lung and brain. Delta-like 1 has been linked to B cell development and differentiation, especially marginal zone and plasma cells, regulation of splenic dendritic cells, and leukemogenesis. Applications Reported: This HMD1-5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HMD1-5 antibody has been tested by flow cytometric analysis on mouse splenocytes and transfected cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
DLL1 (delta-like 1) Monoclonal antibody specifically detects DLL1 (delta-like 1) in Mouse samples. It is validated for Flow Cytometry.Specifications
DLL1 (delta-like 1) | |
Monoclonal | |
0.5 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
Q61483 | |
DLL1 | |
Affinity chromatography | |
RUO | |
13388 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
HMD1-5 | |
Alexa Fluor 488 | |
DLL1 | |
C-Delta-1; Delta; delta like canonical Notch ligand 1; delta like-1; DELTA1; delta-like 1; delta-like 1 (Drosophila); delta-like protein 1; DL1; Dll1; Dll1-derived cell-associated form; Dll1-EC; Dll1-IC; Dll1-intracellular form; Dll1-soluble form; Dll1-TMIC; Drosophila Delta homolog 1; H-Delta-1; LOW QUALITY PROTEIN: delta-like protein 1; OTTHUMP00000017690; UNQ146/PRO172 | |
Armenian Hamster | |
100 μg | |
Primary | |
Mouse | |
Antibody | |
IgG |
For Research Use Only.