missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Disialoganglioside GD3 Mouse anti-Human, Clone: MB3.6, eBioscience™

Mouse Monoclonal Antibody

$120.12 - $322.08

Specifications

Antigen Disialoganglioside GD3
Clone MB3.6
Host Species Murine
Applications Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Microscopy
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122823 Life Technologies
LS14975480
25μg Each for $120.12
501122824 Life Technologies
LS14975482
100μg Each for $322.08
Specifications

Description

The monoclonal antibody MB3.6 recognizes human disialoganglioside GD3, a membrane-bound sialic acid-containing glycosphingolipid. Gangliosides are synthesized in the Golgi apparatus by glycosyltransferases before localizing to the plasma membrane. Gangliosides function as receptors for growth factors and hormones as well as mediating interaction with adhesion molecules at the surface of all cells. GD3 is expressed at low levels in retina pigment cells and melanocytes. Elevated GD3 levels are found in neural stem cells, epithelial-origin tumor cells (cervical, ovarian, prostate, breast, and skin), as well as T-cell leukemic lymphoblasts (T-ALL). The GD3 monoclonal antibody has been reported to fix complement and induce antibody-dependent cytotoxicity of melanoma cell lines.
Description & Specifications

Specifications

Disialoganglioside GD3
Murine
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
MB3.6
Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Microscopy
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL