Diisobutylaluminum hydride reduces chiral ɑ-silyloxy esters to the corresponding enantiomerically-pure hydroxy aldehydes. I t is used in Pd-catalyzed reductive debromination of secondary alkyl bromides, O-Debenzylation and ring opening of perbenzylated furanosides and convenient in situ generation of HZrCp2Cl from ZrCp2Cl2 and DIBAL-H.
Reacts with water.
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. It is sensitive to moisture and air. Store under dry inert gas.
|1M solution in toluene|
Safety and Handling
GHS H Statement
Extremely flammable liquid and vapor.
In contact with water releases flammable gases which may ignite spontaneously.
May be fatal if swallowed and enters airways.
Suspected of damaging fertility or the unborn child.
May cause damage to organs through prolonged or repeated exposure.
Causes severe skin burns and eye damage.
Causes serious eye damage.
May cause drowsiness or dizziness.
GHS P Statement
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
DOTInformation : Transport Hazard Class: 4.3; Packing Group: I; Proper Shipping Name: ORGANOMETALLIC SUBSTANCE, LIQUID, WATER-REACTIVE, FLAMMABLE
RTECSNumber : BD0710000
TSCA : TSCA