A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.
Hydrolyzes in water. Soluble in chloroform and methanol.
Moisture sensitive. Store away from water/moisture, heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Keep it refrigerated. Keep ignition sources away.
|39° to 41°C (0.3mmHg)|
Safety and Handling
GHS H Statement
Causes skin irritation.
Causes serious eye irritation.
GHS P Statement
Wear protective gloves.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Recommended Storage : 2° to 8°C