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Desmin Mouse, Clone: DE-U-10, eBioscience™

Mouse Monoclonal Antibody

$146.52 - $389.40

Specifications

Antigen Desmin
Clone DE-U-10
Host Species Murine
Applications Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Microscopy,Western Blot
Regulatory Status RUO
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122815 Life Technologies
LS14974780
25μg Each for $146.52
501122816 Life Technologies
LS14974782
100μg Each for $389.40
Specifications

Description

The monoclonal antibody DE-U-10 recognizes desmin. Desmin is the protein subunit of class-III intermediate filaments. Desmin is found predominantly in skeletal, cardiac, and smooth muscle. Desmin plays a role in muscle cell development and differentiation, muscle cell architecture and structure, and mitochondrial function. Desmin forms scaffolds around the Z-disk of sarcomeres in muscle cells. Desmin knockout mice exhibit defects in skeletal, smooth, and cardiac muscle and have impaired mitochondrial function. Mutations in Desmin result in conditions such as desmin-related myopathy (DRM), cardiomyopathy dilated type 1I (CMD1I), and neurogenic scapuloperoneal syndrome Kaeser type (Kaeser syndrome).

The DE-U-10 antibody recognizes human, mouse, rat, feline, bovine, goat, hamster, sheep, porcine, rabbit, and chicken desmin. The DE-U-10 antibody will also label tumors derived from muscle tissue, such as leiomyomas and rhabdomyosarcomas.
Description & Specifications

Specifications

Desmin
Murine
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
DE-U-10
Immunocytochemistry,Immunohistochemistry (Formalin/Paraffin),Microscopy,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL