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DDR2 Recombinant Human Protein DFS Item

DDR2 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3870

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Catalog No. PV3870



Description

Description

DDR2 is a member of a subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. DDR1 and DDR2 have been shown to be potently inhibited by Gleevec.
Specifications

Specifications

NP_006173, S642A
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
79.8kDa
80% by SDS-PAGE
–80°C
1 Each
DDR2, TK, NTRKR3
DDR2 was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β- glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 100μM ATP 200μg/mL AXLtide peptide substrate (KKSRGDYMTMQIG) and trace [ 32P]-γ-ATP for 10 minutes at 30°C
Kinases and inhibitors
DDR kinase family
DDR2 Recombinant Human Protein
Human
0.45mg/mL
114294, 4921
DDR2 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Receptor tyrosine kinases
DDR2 Recombinant Human Protein
Kinase assay
Baculovirus
aa 427 to 855
8nmoles of phosphate transferred to AXLtide peptide substrate (KKSRGDYMTMQIG) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
GST Tag
Documents

For Research Use Only. Not for use in diagnostic procedures.