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Thermo Scientific Chemicals D-Mannosamine hydrochloride, 98%

Supplier:  Thermo Scientific Chemicals J6631603

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Catalog No. AAJ6631603



Description

Description

D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer's patches.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
D-Mannosamine hydrochloride is used in the synthesis of non-natural Mannac analogs for the expression of thiols on cell-surface sialic acids. It is also used to investigate and screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. It acts as a precursor of N-propanoyl mannosamine and other N-acyl precursors of sialic acid (N-acyl neuraminic acids). It is a pharmaceutical compound used in the development of mannosylated liposomes for bioadhesive oral drug delivery through M cells of Peyer′s patches.

Solubility
Soluble in water and methanol.

Notes
Hygroscopic. Store in a cool place. Incompatible with strong oxidizing agents.
Specifications

Specifications

D-Mannosamine hydrochloride
168°C (decomposition)
C6H14ClNO5
1 g
2-amino-2-deoxy-d-mannosehydrochloride
CBOJBBMQJBVCMW-DEZHIRTDSA-N
C(C(C(C(C(C=O)N)O)O)O)O.Cl
215.63
215.63
Powder
5505-63-5
White
MFCD00064557
Hygroscopic
Soluble in water and methanol.
−4° (c=2 in Water)
(2R,3S,4R,5S)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
133109008
98%

Chemical Identifiers

5505-63-5
215.63
CBOJBBMQJBVCMW-DEZHIRTDSA-N
133109008
C(C(C(C(C(C=O)N)O)O)O)O.Cl
C6H14ClNO5
MFCD00064557
2-amino-2-deoxy-d-mannosehydrochloride
(2R,3S,4R,5S)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
Safety and Handling

Safety and Handling

P261-P264b-P270-P271-P272-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P330-P333+P313-P362-P501c

H302-H315-H317-H319-H335

EINECSNumber : 226-847-8

TSCA : Yes

Recommended Storage : Keep cold; Store under Argon

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