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Cytokeratin 8 Mouse anti-Human, FITC, Clone: LP3K, eBioscience™

Mouse Monoclonal Antibody

$174.24 - $443.52

Specifications

Antigen Cytokeratin 8
Clone LP3K
Host Species Murine
Gene Alias keratin-8, CK8
Applications Immunocytochemistry,Microscopy
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010083 Life Technologies
LS11993880
25μg Each for $174.24
5010084 Life Technologies
LS11993882
100μg Each for $443.52
Specifications

Description

This LP3K monoclonal antibody reacts with human cytokeratin 8 (K8), a 55kDa member of the family of intermediate filament proteins. Cytokeratin 8 is a type II (or basic) keratin that is expressed in epithelial and carcinoma cells. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. More specifically, studies have demonstrated the involvement of cytokeratin 8 in protection against apoptosis, stress, or injury, as well as regulation of the cell cycle. This keratin is frequently co-expressed with cytokeratin 18, a type I (or acidic) keratin as a heterodimer. Although detected primarily in the cytoplasm of normal healthy cells, cytokeratin 8 has been found to localize to the plasma membrane in some tumor cells. Finally, cytokeratin 8 is phosphorylated on serine 73 in dividing cells.
Description & Specifications

Specifications

Cytokeratin 8
Murine
Immunocytochemistry,Microscopy
FITC
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.5mg/mL
LP3K
keratin-8, CK8
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer