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Cytokeratin 8 Mouse anti-Human, FITC, Clone: LP3K, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $477.05

Specifications

Antigen Cytokeratin 8
Clone LP3K
Host Species Mouse
Gene Alias keratin-8, CK8
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010083

 
affymetrix
11-9938-80
25μg Each for $187.05

5010084

 
affymetrix
11-9938-82
100μg Each for $477.05
Description & Specifications

Specifications

Antigen Cytokeratin 8
Clone LP3K
Host Species Mouse
Gene Alias keratin-8, CK8
Species Reactivity Human
Applications Immunocytochemistry
Applications Microscopy
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This LP3K monoclonal antibody reacts with human cytokeratin 8 (K8), a 55kDa member of the family of intermediate filament proteins. Cytokeratin 8 is a type II (or basic) keratin that is expressed in epithelial and carcinoma cells. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. More specifically, studies have demonstrated the involvement of cytokeratin 8 in protection against apoptosis, stress, or injury, as well as regulation of the cell cycle. This keratin is frequently co-expressed with cytokeratin 18, a type I (or acidic) keratin as a heterodimer. Although detected primarily in the cytoplasm of normal healthy cells, cytokeratin 8 has been found to localize to the plasma membrane in some tumor cells. Finally, cytokeratin 8 is phosphorylated on serine 73 in dividing cells.