missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Cytokeratin 19 Mouse anti-Human, Alexa Fluor® 488, Clone: BA17, eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  Life Technologies LS53989880

Catalog No. 501124663



Description

Description

Description: This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44-kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskel

Cytokeratin 19 is part of a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight from 40-68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial maligcies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. For example, cytokeratin 19 is not expressed in hepatocytes, therefore, it is useful in the identification of liver metastasis.
Specifications

Specifications

Cytokeratin 19
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P08727
CK-19, Keratin-19, K19
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry
BA17
Alexa Fluor® 488
KRT19
Liquid
KRT19
IgG1, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
3880
Documents

For Research Use Only.