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Thermo Scientific™ Lab Vision™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody.

$228.39 - $657.88

Specifications

Antigen Cytokeratin 16 Ab-1
Clone LL025
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunofluorescence
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

MS620P

 
thermo scientific™ lab vision™
MS-620-P
Purified Ab with BSA and Azide 1mL Each for $572.88

MS620P0

 
thermo scientific™ lab vision™
MS-620-P0
Purified Ab with BSA and Azide 100µL Each for $228.39

MS620P1

 
thermo scientific™ lab vision™
MS-620-P1
Purified Ab with BSA and Azide 500µL Each for $387.65

MS620P1ABX

 
thermo scientific™ lab vision™
MS620P1ABX
Ab without BSA/Azide (Frozen) 100µL Each for $506.08

MS620PABX

 
thermo scientific™ lab vision™
MS-620-PABX
Ab without BSA/Azide (Frozen) 200µL Each for $657.88

MS620R7

 
thermo scientific™ lab vision™
MS-620-R7
Ready-to-use for IHC (UVLP) 7mL Each for $327.67
Description & Specifications

Specifications

Antigen Cytokeratin 16 Ab-1
Clone LL025
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Host Species Mouse
Regulatory Status RUO
Research Discipline Cytoskeletal Protein
Type Primary
Immunogen A synthetic peptide from the C-terminus of human cytokeratin 16
Isotype IgG1

Ensure accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody.

Keratins 6 and 16 are expressed in keratinocytes that are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.

Host Species: Mouse

Clone: LL025

Isotype: IgG1

Species Reactivity: Human. Does not react with rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human cytokeratin 16

Molecular Weight: 48 kDa

Positive Control: Squamous cell CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO