Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS620P1ABX

 View more versions of this product

Catalog No. MS620P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen Cytokeratin 16 Ab-1
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone LL025
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Formulation Ab without BSA/Azide (Frozen)
Host Species Mouse
Immunogen A synthetic peptide from the C-terminus of human cytokeratin 16
Isotype IgG1
Quantity 100µL
Regulatory Status RUO
Research Discipline Cytoskeletal Protein
Type Primary

Ensure accurate, reproducible results in immunohistochemistry and immunofluorescence experiments with Thermo Scientific™ Cytokeratin 16 Ab-1, Mouse Monoclonal Antibody.

Keratins 6 and 16 are expressed in keratinocytes that are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.

Host Species: Mouse

Clone: LL025

Isotype: IgG1

Species Reactivity: Human. Does not react with rat. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of human cytokeratin 16

Molecular Weight: 48 kDa

Positive Control: Squamous cell CA

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO