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Thermo Scientific™ Lab Vision™ Cytochrome c Ab-2, Mouse Monoclonal Antibody


Specifically detect Cytochrome c in human, mouse, rat, horse, dog, pigeon, frog and Drosophila samples with Thermo Scientific™ Cytochrome c Ab-2, Mouse Monoclonal Antibody. 

Manufacturer: thermo scientific™ lab vision™  MS1192PABX

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Catalog No. MS1192PABX

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Description & Specifications

Specifications

Cross Reactivity Canine
Cross Reactivity Drosophila
Cross Reactivity Equine
Cross Reactivity Frog
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Pigeon
Cross Reactivity Rat
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Isotype IgG2b kappa
Regulatory Status RUO
Quantity 200µL
Clone 7H8.2C12
Format Concentrated
Antigen Cytochrome c Ab-2
Host Species Mouse
Immunogen Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon cytochrome c
Formulation Ab without BSA/Azide (Frozen)
Type Primary
Classification Monoclonal
Research Discipline Apoptosis
Conjugate Unlabeled
Concentration 1mg/mL
Item Description 200uL; 1mg/mL; Purified w/o BSA, azide

Specifically detect Cytochrome c in human, mouse, rat, horse, dog, pigeon, frog and Drosophila samples with Thermo Scientific™ Cytochrome c Ab-2, Mouse Monoclonal Antibody, which provides accurate, reproducible results.

Cytochrome c is an electron transporting protein that resides within the inter-membrane space of the mitochondria, where it plays a critical role in the process of oxidative phosphorylation and production of cellular ATP. An increasing amount of interest has been directed toward the role which cytocrome c has been demonstrated to play in apoptotic processes. Following exposure to apoptotic stimuli, cytochrome c is rapidly released from the mitochondria into the cytosol, an event which may be required for the completion of apoptosis in some systems. Cytosolic cytochrome c functions in the activation of caspase-3, and ICE family molecule that is a key effector of apoptosis.

Host Species: Mouse

Clone: 7H8.2C12

Isotype: IgG2b/κ

Species Reactivity: Human, Mouse, Rat, Horse, Dog, Pigeon, Frog and Drosophila. Others not known.

Epitope: Not determined

Immunogen: Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon cytochrome c

Molecular Weight: 15 kDa

Positive Control: HeLa cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Not suitable)

Note:

USA: RUO; Int'l: RUO