missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence and immunoprecipitation experiments.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS1249P1ABX

 View more versions of this product

Catalog No. MS1249P1ABX


 

Specifications

Description

Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence and immunoprecipitation experiments with Thermo Scientific™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4, Mouse Monoclonal Antibody.

CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Host Species: Mouse

Clone: M3A7

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 1370-1380

Immunogen: Recombinant protein encoding NBF2 domain of human CFTR

Molecular Weight: 165-170 kDa

Positive Control: Pancreas

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting (Not verified)
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4
Monoclonal
1mg/mL
Ab without BSA/Azide (Frozen)
Murine
IgG1
RUO
Monoclonal
Immunofluorescence,Immunohistochemistry (Paraffin),Immunoprecipitation
M3A7
Unlabeled
Concentrated
Recombinant protein encoding NBF2 domain of human CFTR
100μL
Primary
Human,Murine,Rat