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Thermo Scientific™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments.

$293.16 - $1,440.59

Specifications

Antigen Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3
Clone L12B4
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Immunofluorescence
View More Specs
Products
Catalog Number Mfr. No. Concentration Quantity Price Quantity    

MS1248P

 
thermo scientific™
MS-1248-P
200�g/mL 1mL Each for $1,360.08

MS1248P0

 
thermo scientific™
MS-1248-P0
200�g/mL 100µL Each for $293.16

MS1248P1

 
thermo scientific™
MS-1248-P1
200�g/mL 500µL Each for $833.63

MS1248P1ABX

 
thermo scientific™
MS1248P1ABX
1mg/mL 100µL Each for $940.82

MS1248PABX

 
thermo scientific™
MS1248PABX
1mg/mL 200µL Each for $1,440.59
Description & Specifications

Specifications

Antigen Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3
Clone L12B4
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Immunofluorescence
Applications Immunoprecipitation
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Type Primary
Immunogen Recombinant protein encoding NBF1 domain of human CFTR
Isotype IgG1

Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments with Thermo Scientific™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3, Mouse Monoclonal Antibody.

CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Host Species: Mouse

Clone: L12B4

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 386-412

Immunogen: Recombinant protein encoding NBF1 domain of human CFTR

Molecular Weight: 165-170 kDa

Positive Control: Pancreas

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not verified)
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO