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Epredia™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments.
Supplier: Epredia™ MS1248P0
Description
CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Host Species: Mouse
Clone: L12B4
Isotype: IgG1
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: aa 386-412
Immunogen: Recombinant protein encoding NBF1 domain of human CFTR
Molecular Weight: 165-170 kDa
Positive Control: Pancreas
Cellular Localization: Membrane
Recommended for:
- Western Blotting (Not verified)
- Immunofluorescence
- Immunoprecipitation
Note:
USA: RUO; Int'l: RUO
Specifications
| Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3 | |
| Monoclonal | |
| 200μg/mL | |
| Mouse | |
| 100 μL | |
| Primary | |
| Concentrated |
| Immunofluorescence, Immunoprecipitation | |
| L12B4 | |
| Unconjugated | |
| Recombinant protein encoding NBF1 domain of human CFTR | |
| RUO | |
| Human, Mouse, Rat | |
| IgG1 |