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Thermo Scientific™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments.

Manufacturer:  Thermo Scientific™ MS1248P1ABX

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Catalog No. MS1248P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in immunofluorescence and immunoprecipitation experiments with Thermo Scientific™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3, Mouse Monoclonal Antibody.

CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

Host Species: Mouse

Clone: L12B4

Isotype: IgG1

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: aa 386-412

Immunogen: Recombinant protein encoding NBF1 domain of human CFTR

Molecular Weight: 165-170 kDa

Positive Control: Pancreas

Cellular Localization: Membrane

Recommended for:

  • Western Blotting (Not verified)
  • Immunofluorescence
  • Immunoprecipitation

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-3
Monoclonal
1mg/mL
Human,Mouse,Rat
Murine
IgG1
RUO
Monoclonal
Immunofluorescence,Immunoprecipitation
L12B4
Unlabeled
Concentrated
Recombinant protein encoding NBF1 domain of human CFTR
100μL
Primary
Human,Murine,Rat