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Thermo Scientific™ Lab Vision™ Cyclin E Ab-5, Mouse Monoclonal Antibody

Obtain accurate, reproducible results in immunohistochemistry and immunoprecipitation experiments with Thermo Scientific™ Cyclin E Ab-5, Mouse Monoclonal Antibody.

$265.53 - $1,120.55

Specifications

Antigen Cyclin E Ab-5
Clone 13A3
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Immunohistochemistry (Paraffin)
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

MS1060R7

 
thermo scientific™ lab vision™
MS-1060-R7
7mL Each for $705.10

MS1060S

 
thermo scientific
MS-1060-S
1mL Each for $1,120.55

MS1060S0

 
thermo scientific™ lab vision™
MS-1060-S0
100µL Each for $265.53

MS1060S1

 
thermo scientific™ lab vision™
MS-1060-S1
500µL Each for $746.67
Description & Specifications

Specifications

Antigen Cyclin E Ab-5
Clone 13A3
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Applications Immunohistochemistry (Paraffin)
Applications Immunoprecipitation
Classification Monoclonal
Conjugate Unlabeled
Cross Reactivity Human
Host Species Mouse
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary
Immunogen Recombinant human cyclin E protein
Isotype IgG2a kappa

Obtain accurate, reproducible results in immunohistochemistry and immunoprecipitation experiments with Thermo Scientific™ Cyclin E Ab-5, Mouse Monoclonal Antibody.

Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Host Species: Mouse

Clone: 13A3

Isotype: IgG2a/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human cyclin E protein

Molecular Weight: Doublet of 50 kDa and a single band of 42 kDa

Positive Control: SKBR3 and LS174T cells; Breast CA or placenta

Cellular Localization: Nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Immunoprecipitation (Native and Denatured)

Note:

USA: RUO; Int'l: RUO