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Thermo Scientific™ Lab Vision™ Cyclin E Ab-1, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and kinase assay experiments.

$263.20 - $1,083.73

Specifications

Antigen Cyclin E Ab-1
Concentration 1mg/mL
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
View More Specs
Products
Catalog Number Mfr. No. Formulation Quantity Price Quantity    

RB012P

 
thermo scientific™ lab vision™
RB-012-P
Purified Ab with BSA and Azide 1mL Each for $992.49

RB012P0

 
thermo scientific™ lab vision™
RB-012-P0
Purified Ab with BSA and Azide 100µL Each for $263.20

RB012P1

 
thermo scientific™ lab vision™
RB-012-P1
Purified Ab with BSA and Azide 500µL Each for $663.59

RB012P1ABX

 
thermo scientific™ lab vision™
RB012P1ABX
Ab without BSA/Azide (Frozen) 500µL Each for $749.27

RB012PABX

 
thermo scientific™ lab vision™
RB-012-PABX
Ab without BSA/Azide (Frozen) 1mL Each for $1,083.73
Description & Specifications

Specifications

Antigen Cyclin E Ab-1
Concentration 1mg/mL
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
Applications Western Blotting
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Rabbit
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary
Immunogen A synthetic peptide derived from the C-terminus of human cyclin E
Isotype IgG

Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and kinase assay experiments with Thermo Scientific™ Cyclin E Ab-1, Rabbit Polyclonal Antibody.

Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not known.

Epitope: C-terminal

Immunogen: A synthetic peptide derived from the C-terminus of human cyclin E

Molecular Weight: 50 kDa (in normal tissues), and up to 12 proteins ranging 20-50 kDa (in tumor samples)

Positive Control: SKBR3 and MAD109 cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Kinase Assay

Note:

USA: RUO; Int'l: RUO