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CXCL10 (IP-10) Mouse anti-Human, PE, Clone: 4NY8UN, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $448.05

Specifications

Antigen CXCL10 (IP-10)
Clone 4NY8UN
Host Species Mouse
Gene Alias Interferon Inducible Protein-10, CXC Motif Chemokine 10
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122455

 
affymetrix
12974441
25 tests Each for $187.05

501122456

 
affymetrix
12974442
100 tests Each for $448.05
Description & Specifications

Specifications

Antigen CXCL10 (IP-10)
Clone 4NY8UN
Host Species Mouse
Gene Alias Interferon Inducible Protein-10, CXC Motif Chemokine 10
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

This 4NY8UN monoclonal antibody reacts with human CXCL10. CXCL10, also known as Interferon Inducible Protein-10 (IP-10), is a member of the CXC family of chemokines. It is secreted by monocytes, epithelial cells, and endothelial cells in response to IFN gamma or other pro-inflammatory cytokines and stimuli. CXCL10 signaling is mediated by the G protein-coupled receptor CXCR3, which is expressed on activated T cells and plays an important role in directing the migration of T cells, especially during Th1 responses. In addition to its chemotactic functions, CXCL10 is a potent inhibitor of angiogenesis and tumor growth and modulates expression of adhesion molecules. Elevated levels of CXCL10 are observed in response to allergic inflammation, various infections, and Alzheimer’s disease.