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CX3CR1 Rat anti-Human, APC, Clone: 2A9-1, eBioscience™

Rat Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen CX3CR1
Clone 2A9-1
Host Species Rat
Gene Alias Chemokine C-X3-C receptor 1, V28
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123176

 
affymetrix
17609941
25 tests Each for $172.55

501123177

 
affymetrix
17609942
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CX3CR1
Clone 2A9-1
Host Species Rat
Gene Alias Chemokine C-X3-C receptor 1, V28
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

This 2A9-1 monoclonal antibody reacts with human CX3CR1, which is the receptor for fractalkine, a transmembrane chemokine of the CX3C family. CX3CR1 is a seven transmembrane G protein-coupled receptor expressed on CD16+ NK cells, T cells (e.g. CD8+, CD4+, and gamma/delta), and monocytes. In non-immune cells, CX3CR1 has been found on osteoclast precursors and microglia. Little to no CX3CR1 surface expression can be detected on B cells and granulocytes. Together, fractalkine and its receptor mediate cell-cell adhesion and chemotaxis of NK cells, T cells, and monocytes. The expression of CX3CR1 has also been correlated with high levels of intracellular perforin and granzyme B.