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R&D Systems Cultrex PathClear BME, Type 2, with Phenol Red Storage Buffer

Soluble form of basement membrane purified from Engelbreth-Holm-Swarm (EHS) tumor

$192.79 - $289.17

Products
Catalog Number Mfr. No. Quantity Price Quantity    

35-320-0502P

 
r&d systems
3532-005-02P
5mL Each for $192.79

35-320-1002P

 
r&d systems
3532-010-02P
2 x 5mL Each for $289.17
Description & Specifications

Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma. Basement membranes are degraded and regenerated during development and wound healing. They not only support cells and cell layers, but they also play an essential role in tissue organization that affects cell adhesion, migration, proliferation, and differentiation. Basement membranes provide major barriers to invasion by metastatic tumor cells.

The major components of BME include laminin, collagen IV, entactin, and heparin sulfate proteoglycan
BME can be used in a multiple applications, under a variety of cell culture conditions, for maintaining growth or promoting differentiation of primary endothelial, epithelial, smooth muscle and stem cells
BME can also be utilized in cell attachment, neurite outgrowth, angiogenesis, in vitro cell invasion and in vivo tumorigenicity assays
Higher tensile strength than standard BME
DMEM with phenol red storage buffer, with 10μg/mL gentamycin sulfate
Sterility tested

Applications:

cell culture, stem cell, tumorgraft