Please login to your online account to display your discounted pricing

Alfa Aesar™ (-)-Cotinine, 98%

$84.41 - $198.51

Chemical Identifiers

Chemical Name or Material (-)-Cotinine
CAS 486-56-6
Molecular Formula C10H12N2O
Formula Weight 176.22g/mol
MDL Number MFCD00077696
Beilstein 83099
Merck Index 14,2553
Synonym (S)-(-)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone
View More Specs
Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAL1187303

 
alfa aesar™
L11873-03
1g Each for $198.51

AAL11873MD

 
alfa aesar™
L11873-MD
250mg Each for $84.41
Description & Specifications

Specifications

Melting Point 34° to 39°C
Boiling Point 145° to 147°C (3mmHg)
Quantity 1g
Flash Point >110°C (230°F)
Optical Rotation −20° (c=1 in Ethanol)
Chemical Name or Material (-)-Cotinine
CAS 486-56-6
Assay 98%
Molecular Formula C10H12N2O
Formula Weight 176.22g/mol
MDL Number MFCD00077696
Beilstein 83099
Merck Index 14,2553
Synonym (S)-(-)-1-Methyl-5-(3-pyridyl)-2-pyrrolidinone
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage 2° to 8°C
RTECS Number GN1925500

Applications
(-)-Cotinine is used to activate a subpopulation of α3/ α6β2 nAChRs in monkey striatum. It binds nicotinic- and muscarinic-type acetylcholine receptors with minimal receptor desensitization and demonstrates antipsychotic drug-like properties in behavioral models, neuroprotective properties in neurodegenerative disease models, and enhances attention in a delayed matching-to-sample task.

Solubility
Not miscible or difficult to mix in water. Soluble in dimethyl sulfoxide (100 mM), ethanol (50 mg/ml, yielding a clear, faint yellow to yellow solution), methanol and chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature is 2 - 8°C.

Safety and Handling

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

2° to 8°C