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Corning™ Matrigel™ GFR Membrane Matrix

Produces a biologically active matrix material resembling the mammalian cellular basement matrix. Corning™ Matrigel™ GFR Basement Membrane Matrix provides a physiologically relevant environment for studies of cell morphology, biochemical function, migration, invasion, and gene expression.

Manufacturer: corning™  354230

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Catalog No. CB-40230


Description & Specifications


For Use With (Application) Suitable for applications that require a highly defined basement membrane preparation.
Packaging N/A
Product Type Growth factor reduced basement membrane matrix
Quantity 10mL
Source Engelbreth-Holm-Swarm Mouse Tumor
Storage Requirements -20°C


  • Tested for the ability to promote neurite outgrowth of chick dorsal root ganglia cells
  • Tested and found negative for bacteria, fungi, and mycoplasma
  • Source: Engelbreth-Holm-Swarm (EHS) mouse tumor, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparin sulfate proteoglycans, entactin/nidogen, and a number of growth factors
  • Base formulation: Dulbecco's Modified Eagle's Medium with 50μg/mL gentamycin, with or without Phenol Red
  • Solubilized basement membrane preparations polymerize at room temperature
  • Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testing
  • Extensive PCR testing is performed to screen for a number of pathogens
  • Tested and found negative for bacteria, fungi, and mycoplasma
  • Protein concentrations determined by Lowry method
  • Endotoxin units measured by Limulus Amoebocyte Lysate assay
  • Matrigel Matrix gel stability is tested for a period of 14 days at 37°C
  • Biological activity is determined for each lot using a neurite outgrowth assay
Application: • Cell Growth and Differentiation • Metabolism/Toxicology Studies • Invasion Assays • In Vitro and In Vivo Angiogenesis Assays • In Vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice