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Connexin 32 Mouse, Alexa Fluor 488, Clone: Connexin32 (2A), eBioscience™

Mouse Monoclonal Antibody

$158.05 - $419.05

Specifications

Antigen Connexin 32
Clone Connexin32 (2A)
Host Species Mouse
Gene Alias Gap junction protein beta-1
Species Reactivity Chicken, Human, Mouse, Rat
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124631

 
affymetrix
53975980
25μg Each for $158.05

501124632

 
affymetrix
53975982
100μg Each for $419.05
Description & Specifications

Specifications

Antigen Connexin 32
Clone Connexin32 (2A)
Host Species Mouse
Gene Alias Gap junction protein beta-1
Species Reactivity Chicken, Human, Mouse, Rat
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Applications Microscopy
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The Connexin32 monoclonal antibody recognizes human, mouse, rat, and chicken Connexin 32. Connexins are a family of integral membrane proteins that form gap junction channels, which function to facilitate direct cell-cell communication. Gap junctions are comprised of two hemichannels, or connexons, which are made up of six connexin proteins. Over 20 connexin proteins have been identified and each combine to form either homomeric or heteromeric channels with different functional properties. Connexin 32 is expressed by myelin, neurons, oligodendrocytes, and hepatocytes, and plays a role in the development of ovarian follicles. Connexin 32 expression also plays a role in disease progression in chronic multiple sclerosis and experimental autoimmune encephalomyelitis. Mutations in the Connexin 32 gene, GJB1, result in a form of Charcot-Marie-Tooth disease which is characterized by peripheral nerve dysfunction.