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Alfa Aesar™ Clotrimazole

Specific inhibitor of calcium-activated potassium channels

$97.01 - $314.59

Chemical Identifiers

CAS 23593-75-1
Molecular Formula C22H17ClN2
Molecular Weight (g/mol) 344.842
MDL Number MFCD00057220
InChI Key VNFPBHJOKIVQEB-UHFFFAOYSA-N
Synonym 1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
PubChem CID 2812
ChEBI CHEBI:3764
IUPAC Name 1-[(2-chlorophenyl)-diphenylmethyl]imidazole
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
AAJ6389506 View Documents Alfa Aesar™
J6389506
5g Each for $97.01
 
AAJ6389514 View Documents Alfa Aesar™
J6389514
25g Each for $314.59
 
Description

Description

Applications
Clotrimazole is an imidazole derivative and an antifungal compound and a CYP (cytochrome P450) inhibitor. Clotrimazole has been shown to block the intermediate-conductance, IK1 channels (Ca2+ activated K+ channels), in cells such as erythrocytes. In vitro studies of various yeast strains have demonstrated susceptibility to clotrimazole. Clotrimazole is an activator of MB67 and an inhibitor of CYP3A4 and CYP51A1.

Solubility
Soluble in chloroform, DMSO, DMF and alcohols

Notes
Store at room temperature. Incompatible with oxidizing agents.
Specifications

Chemical Identifiers

23593-75-1
344.842
VNFPBHJOKIVQEB-UHFFFAOYSA-N
2812
1-[(2-chlorophenyl)-diphenylmethyl]imidazole
C22H17ClN2
MFCD00057220
1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
CHEBI:3764
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4

Specifications

23593-75-1
MFCD00057220
1-[(2-Chlorophenyl)diphenylmethyl]-1H-imidazole; 1-(o-Chlorotrityl)imidazole
VNFPBHJOKIVQEB-UHFFFAOYSA-N
1-[(2-chlorophenyl)-diphenylmethyl]imidazole
2812
344.84
White
5g
C22H17ClN2
14,2417
Soluble in chloroform, DMSO, DMF and alcohols
C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CN=C4
344.842
CHEBI:3764
Powder
141°C to 149°C
Clotrimazole
Safety and Handling

Safety and Handling

GHS H Statement
H302-H315-H319
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.

GHS P Statement
P280-P305+P351+P338-P362-P301+P312-P321-P501a
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Take off contaminated clothing and wash before reuse.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
Specific treatment (see label).
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

RTECSNumber : NI4377000