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CLK4 Recombinant Human Protein DFS Item

CLK4 Recombinant Human Protein

Manufacturer:  Life Technologies LSPV3839

Catalog No. PV3839



Description

Description

CLK4 belongs to the CDC2-like protein kinase (CLK) family. It can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus is thought to be involved in the regulation of alternative splicing.
Specifications

Specifications

NP_065717
Pharma and biopharma, protein assays and analysis, target and lead identification and validation
85kDa
90% by SDS-PAGE
–80°C
1 Each
CLK4
CLK4 was pre-diluted in enzyme dilution buffer and assayed in 25mM Tris (pH 7.5), 10mM MgCl2, 0.5mM EGTA, 0.5mM Na3VO4, 5mM β-glycerophosphate, 2.5mM DTT, 0.01% Triton™ X-100, 200μM ATP, 100μM RS domain derived peptide substrate (GRSRSRSRSR) and trace [32P]-γ-ATP for 10 minutes at 30°C
Kinase and inhibitors
CLK
44nmoles of phosphate transferred to RS domain derived peptide substrate (GRSRSRSRSR) per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 8.33μg/mL
GST Tag
0.24mg/mL
57396, 7040
CLK4 Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
CLK4 Recombinant Human Protein
Kinase assay
Baculovirus
CLK4 Recombinant Human Protein
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.