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Tocris™ CITCO

Selective CAR agonist

$165.79 - $700.43

Specifications

Product Type CITCO
Inhibitors CITCO
Molecular Weight 436.74
Purity >98
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 Disclaimers

For Research Use Only

Products
Catalog Number Mfr. No. Quantity Price Quantity    

368310R

 
tocris™
3683/10
10mg Each for $165.79

368350R

 
tocris™
3683/50
50mg Each for $700.43
Description & Specifications

Specifications

Product Type CITCO
Inhibitors CITCO
Molecular Weight 436.74
Purity >98

Constitutive androstane receptor (CAR) agonist (EC50 = 49nM). Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ERα, ERβ, PPAR, RAR, FXR, VDR and THR. Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro.

  • Chemical Name: 6-(4-Chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime
  • Formula: C19H12Cl3N3OS
  • CAS Number: 338404-52-7
  • Solubility: Soluble to 50mM in DMSO and to 5mM in ethanol
  • Purity: >98