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Alfa Aesar™ cis-4-Hydroxy-L-proline, 99%

$215.55 - $717.68

Chemical Identifiers

Chemical Name or Material cis-4-Hydroxy-L-proline
CAS 618-27-9
Molecular Formula C5H9NO3
Formula Weight 131.13g/mol
MDL Number MFCD00064319
Synonym (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid; H-cis-Hyp-OH
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAH2719403

 
alfa aesar™
H27194-03
1g Each for $717.68

AAH27194MD

 
alfa aesar™
H27194-MD
250mg Each for $215.55
Description & Specifications

Specifications

Quantity 1g
Melting Point ≈250°C
Quantity 1g
Optical Rotation −59° (c=2 in Water)
Chemical Name or Material cis-4-Hydroxy-L-proline
CAS 618-27-9
Assay 99%
Molecular Formula C5H9NO3
Formula Weight 131.13g/mol
MDL Number MFCD00064319
Synonym (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid; H-cis-Hyp-OH
TSCA TSCA

Applications
cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.

Solubility
Soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.