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Cimetidine, 98+%, Thermo Scientific Chemicals

H2 histamine receptor antagonist

Supplier:  Thermo Scientific Chemicals J6282509

 View more versions of this product

Catalog No. AAJ6282509



Description

Description

Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent and is an activator of Nischarin. Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency).

Notes
Store away from heat and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Specifications

Specifications

Cimetidine
139°C to 144°C
C10H16N6S
10 g
cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine
AQIXAKUUQRKLND-UHFFFAOYSA-N
1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
2756
252.34
Powder
51481-61-9
White
MFCD00133296
14,2279
Soluble to 50 mM in water and to 100 mM in DMSO,solubility in HCl (almost transparency).
CC1=C(N=CN1)CSCCNC(=NC)NC#N
252.34
CHEBI:3699
≥98%

Chemical Identifiers

51481-61-9
252.34
AQIXAKUUQRKLND-UHFFFAOYSA-N
2756
1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
C10H16N6S
MFCD00133296
cimetidine, tagamet, tametin, eureceptor, cimetag, acinil, tratul, cimetidina, dyspamet, ulcedine
CHEBI:3699
CC1=C(N=CN1)CSCCNC(=NC)NC#N
Safety and Handling

Safety and Handling

GHS H Statement
H360
May damage fertility or the unborn child.

P201-P202-P281-P308+P313-P501c

H360

EINECSNumber : 257-232-2

RTECSNumber : MF0035500

TSCA : No

Recommended Storage : Keep cold

SDS
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