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Alfa Aesar™ Chlorambucil, 98%

Alkylates DNA; induces apoptosis in chronic lymphocytic leukemia cells

Chemical Identifiers

Chemical Name or Material Chlorambucil
CAS 305-03-3
Molecular Formula C14H19Cl2NO2
Formula Weight 304.21g/mol
MDL Number MFCD00021783
UN Number UN2811
Beilstein 999011
Merck Index 14,2073
Synonym 4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid
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Products
Catalog Number Mfr. No. Quantity Price Quantity    

AAJ61964ME

 
alfa aesar™
J61964-ME
500mg CALL N/A N/A
 Please call Customer Service at 1-800-234-7437 or send an email to help@thermofisher.com for assistance.
Description & Specifications

Specifications

Color Pale Brown
Melting Point 66° to 67°C
Quantity 500mg
Chemical Name or Material Chlorambucil
CAS 305-03-3
Physical Form Powder
Assay 98%
Molecular Formula C14H19Cl2NO2
Formula Weight 304.21g/mol
MDL Number MFCD00021783
UN Number UN2811
Beilstein 999011
Merck Index 14,2073
Synonym 4-(4-[Bis(2-chloroethyl)amino]phenyl)butyric acid
Health Hazard 1 Danger
Health Hazard 2 GHS H Statement
H301-H350-H315-H319-H335
Toxic if swallowed.
May cause cancer.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P301+P310-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Recommended Storage 2° to 8°C
DOT Information Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
RTECS Number ES7525000

Applications
Chlorambucil is an anti-cancer drug that alkylates DNA and induces apoptosis. It can be covalently coupled to monoclonal anticarcinombryonic antigen.

Solubility
Soluble in ether, and ethanol:chloroform:acetone (3:5:4) (warm). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.

Safety and Handling

Danger

GHS P Statement
P261-P280-P301+P310-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H301-H350-H315-H319-H335
Toxic if swallowed.
May cause cancer.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

2° to 8°C