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Alfa Aesar™ CHAPS, Electrophoresis Grade


Quantity 25g

Manufacturer: alfa aesar™  J67359-14

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Catalog No. AAJ6735914

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Description & Specifications

Chemical Identifiers

Color White
Melting Point 156 to 158°C
Quantity 25g
Sensitivity Hygroscopic
Chemical Name or Material CHAPS
CAS 75621-03-3
Purity Grade Electrophoresis Grade
Physical Form Powder
Formula Weight 614.88g/mol
MDL Number MFCD00012116
Synonym 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
Health Hazard 1 Warning
Health Hazard 2 GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3 GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Specifications

Chemical Name or Material CHAPS
CAS 75621-03-3
Purity Grade Electrophoresis Grade
Formula Weight 614.88g/mol
MDL Number MFCD00012116
Synonym 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

Applications
CHAPS is often used as a detergent in the solubilization and purification of membrane proteins for several advantageous reasons. CHAPS detergent is non-denaturing to membrane proteins, can solubilize proteins, disaggregate protein-protein interactions. CHAPS is also useful in ion exchange chromatography and isoelectric focusing as it is zwitterionic and does not exhibit a net charge between pH 2 to 12. It is suitable for isolation of membrane proteins with the following features such as sufficient protein solubilization capability, no denaturing or inactivation of proteins, no interference with protein activities, no precipitation at 4°C, appropriate critical micelle concentrations (CMC) and micelle size, no absorption in the UV region, no toxicity and availability of detergent detection methods.

Solubility
Soluble in water (10 mg/ml). Soluble in DMF and hot methanol.

Notes
Hygroscopic. Store away from water/moisture and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Accessories

Warning

GHS P Statement
P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapors/spray.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
Store locked up.
Dispose of contents/container in accordance with local/regional/national/international regulations.

GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.