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Alfa Aesar™ CGS 21680 hydrochloride, 99%

An A2A Adenosine receptor agonist

Chemical Identifiers

Chemical Name or Material CGS 21680 hydrochloride
CAS 124182-57-6
Molecular Formula C23H29N7O6·HCl
Formula Weight 535.98
MDL Number MFCD11045878
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5mg CALL N/A N/A
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Description & Specifications


Formula Weight 535.98
Chemical Name or Material CGS 21680 hydrochloride
CAS 124182-57-6
MDL Number MFCD11045878
Assay 99%
Physical Form Solid
Color White
Quantity 5mg
Molecular Formula C23H29N7O6·HCl

CGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity.

Soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin.

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.