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CDK8/Cyclin C Recombinant Human Protein DFS Item

CDK8/Cyclin C Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4345

 View more versions of this product

Catalog No. PV4345

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Description

Description

CDK8 phosphorylates the carboxy-terminal domain of the largest subunit of RNA polymerase II. This protein is coexpressed and copurified with CyclinC.
Specifications

Specifications

NP_001251, NP_005181
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
Frozen
CDK8/cyclin C Recombinant Human Protein
1mg
For research use only. Not for use in diagnostic procedures
CDK8/cyclin C, CCNC
The ability of CDK8/cyclin C to bind the ATP competitor kinase tracer 236 (PV5592) was demonstrated for this lot of CDK8/cyclin C in the LanthaScreen™ Eu kinase binding assay. Increasing amounts of kinase tracer 236 (PV5592) were incubated with 5nM CDK8/cyclin C and 2nM Eu-anti-HIS antibody (PV5596) in kinase buffer A (PV3189) with and without the presence of 10μM Staurosporine as the competitor for the kinase tracer
Baculovirus
CDK8/cyclin C Recombinant Human Protein
His Tag
0.34mg/mL
Frozen
97kDa
80% by SDS-PAGE
–80°C
1 Each
CDK8/cyclin C Recombinant Human Protein
Kinase assay
CDK and CHK
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.