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CDK8/Cyclin C Recombinant Human Protein DFS Item

CDK8/Cyclin C Recombinant Human Protein

Manufacturer:  Life Technologies LSPV4402

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Catalog No. PV4402



Description

Description

CDK8 phosphorylates the carboxy-terminal domain of the largest subunit of RNA polymerase II. This protein is coexpressed and copurified with CyclinC.
Specifications

Specifications

NP_001251, NP_005181
Cell viability, proliferation and function, pharma and biopharma, protein assays and analysis, target and lead identification and validation
CDK8/cyclin C Recombinant Human Protein
10μg
For research use only. Not for use in diagnostic procedures
Serine/threonine kinase
CDK8/cyclin C Recombinant Human Protein
Kinase assay
Baculovirus
CDK8/cyclin C Recombinant Human Protein
His Tag
0.34mg/mL
57.4/39.6, 97kDa
80% by SDS-PAGE
–80°C
1 Each
CDK8/cyclin C, CCNC
The ability of CDK8/cyclin C to bind the ATP competitor kinase tracer 236 (PV5592) was demonstrated for this lot of CDK8/cyclin C in the LanthaScreen™ Eu kinase binding assay. Increasing amounts of kinase tracer 236 (PV5592) were incubated with 5nM CDK8/cyclin C and 2nM Eu-anti-HIS antibody (PV5596) in kinase buffer A (PV3189) with and without the presence of 10μM Staurosporine as the competitor for the kinase tracer
Kinase and inhibitors
CDK and CHK
Human
Documents

For Research Use Only. Not for use in diagnostic procedures.