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Invitrogen™ CDK2/cyclin O Recombinant Human Protein DFS Item

CDK2/cyclinO is a member of the cyclin dependent protein kinase family complexed to CyclinO. Recombinant full-length human CDK2/Cyclin O was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Manufacturer:  Invitrogen™ LSPV6288

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Catalog No. PV6288



Description

Description

CyclinO was used as a specific protein isoform name for the UNG gene which is localized exclusively in the nucleus. In addition, CyclinO was reported to shows significant uracil-DNA glycosylase activity. CDK2/cyclinO protein levels increase during G1 phase and the protein is turned over during the course of cell cycle.

  • Validated in LanthaScreen™ Kinase Binding Assay
  • Protocols available for simple use and optimized performance
  • Multiple pack sizes available for convenient use
Specifications

Specifications

Target & Lead Identification & Validation|Kinase Biology|Kinase Proteins & Expression Reagents|Protein Biology|Enzyme & Protein Activity Assays|Kinase Activity|Protein Assays and Analysis|Industrial & Applied Science|Pharma & Biopharma
60.2/64.4kDa
Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws.
Kinase Assay
Yes
50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol
1mg
CDK2: p33 (CDK2) CyclinO: CCNO, CCNU, UDG2
Human
GST Tag
Documents