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Thermo Scientific™ Lab Vision™ Cdk2 Ab-4, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in western blotting, immunofluorescence and immunoprecipitation experiments with Thermo Scientific™ Cdk2 Ab-4, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS617P1ABX

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Catalog No. MS617P1ABX

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Description & Specifications

Specifications

Antigen Cdk2 Ab-4
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone 2B6 + 8D4
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Concentrated
Host Species Mouse
Immunogen Human recombinant cdk2 protein
Isotype IgG2a IgG2b
Quantity 100µL
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary

Ensure accurate, reproducible results in Western Blotting, Immunofluorescence and Immunoprecipitation experiments with Thermo Scientific™ Cdk2 Ab-4, Mouse Monoclonal Antibody.

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Host Species: Mouse

Clone: 2B6 + 8D4

Isotype: IgG2b (2B6) + IgG2a (8D4)

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant Cdk2 protein

Molecular Weight: 33 kDa

Positive Control: HeLa cells

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured only)

Note:

USA: RUO; Int'l: RUO