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Thermo Scientific™ Lab Vision™ Cdk2 Ab-4, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting, immunofluorescence and immunoprecipitation experiments with Thermo Scientific™ Cdk2 Ab-4, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS617P1ABX

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Catalog No. MS617P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in Western Blotting, Immunofluorescence and Immunoprecipitation experiments with Thermo Scientific™ Cdk2 Ab-4, Mouse Monoclonal Antibody.

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Host Species: Mouse

Clone: 2B6 + 8D4

Isotype: IgG2b (2B6) + IgG2a (8D4)

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: Not determined

Immunogen: Human recombinant Cdk2 protein

Molecular Weight: 33 kDa

Positive Control: HeLa cells

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Denatured only)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

Cdk2 Ab-4
Monoclonal
1mg/mL
Concentrated
Human recombinant cdk2 protein
100μL
Cell Cycle
Monoclonal
Immunofluorescence,Immunoprecipitation,Western Blotting
2B6 + 8D4
Unlabeled
Murine
IgG2a IgG2b
RUO
Primary
Human,Murine,Rat