Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ Cdk2 Ab-1, Mouse Monoclonal Antibody


Accurately detect Cdk2 in human, mouse and rat tissues with Thermo Scientific™ Cdk2 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS459P1ABX

 View more versions of this product

Catalog No. MS459P1ABX

  • / Each
 

Description & Specifications

Specifications

Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blotting
Regulatory Status RUO
Immunogen Human recombinant cdk2 protein
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Antigen Cdk2 Ab-1
Isotype IgG2b
Host Species Mouse
Format Concentrated
Clone 2B6
Quantity 100µL
Type Primary
Formulation Ab without BSA/Azide (Frozen)
Concentration 1mg/mL
Classification Monoclonal
Conjugate Unlabeled
Research Discipline Cell Cycle

Accurately detect Cdk2 in human, mouse and rat tissues with Thermo Scientific™ Cdk2 Ab-1, Mouse Monoclonal Antibody.

p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as is cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.

Host Species: Mouse

Clone: 2B6

Isotype: IgG2b

Species Reactivity: Human, Mouse and Rat.

Epitope: Not determined

Immunogen: Human recombinant Cdk2 protein

Molecular Weight: 33 kDa

Positive Control: HeLa cells, Tonsil

Cellular Localization: Cytoplasmic and nuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence

Note:

USA: RUO; Int'l: RUO