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Thermo Scientific™ Lab Vision™ CDC6 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ CDC6 Ab-1, Mouse Monoclonal Antibody.

$254.86 - $1,418.22

Specifications

Antigen CDC6 Ab-1
Clone DCS-180
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
View More Specs
Products
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity    

MS867B

 
thermo scientific™ lab vision™
MS-867-B
200�g/mL Biotin 1mL Each for $1,418.22

MS867B0

 
thermo scientific™ lab vision™
MS-867-B0
200�g/mL Biotin 100µL Each for $344.96

MS867B1

 
thermo scientific™ lab vision™
MS-867-B1
200�g/mL Biotin 500µL Each for $939.43

MS867P

 
thermo scientific™ lab vision™
MS-867-P
200�g/mL Unlabeled 1mL Each for $1,097.53

MS867P0

 
thermo scientific™ lab vision™
MS-867-P0
200�g/mL Unlabeled 100µL Each for $254.86

MS867P1

 
thermo scientific™ lab vision™
MS-867-P1
200�g/mL Unlabeled 500µL Each for $722.57

MS867P1ABX

 
thermo scientific™ lab vision™
MS867P1ABX
1mg/mL Unlabeled 100µL Each for $802.27

MS867PABX

 
thermo scientific™ lab vision™
MS-867-PABX
1mg/mL Unlabeled 200µL Each for $1,193.90
Description & Specifications

Specifications

Antigen CDC6 Ab-1
Clone DCS-180
Applications Immunoprecipitation
Applications Western Blotting
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary
Immunogen Recombinant human CDC6 protein
Isotype IgG1

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ CDC6 Ab-1, Mouse Monoclonal Antibody.

The replication licensing system acts to ensure that no section of the genome is replicated more than once in a single cell cycle. The origin recognition complex (ORC) and CDC6/CDC18 are needed on chromatin before the licensing reaction can take place. During the transition from a growth-arrested to a proliferative state, transcription of mammalian CDC6 is regulated by the cell cycle transcription factor (E2F protein). Immunoblots show that minichromosome maintenance (MCM) proteins are not associated with chromatin. Competence of G1 phase nuclei to replicate in vitro coincides with maximum CDC6 accumulation and MCM protein binding to chromatin in vivo. Antibodies against CDC6 and MCM5 stain abnormal (neoplastically transformed) cells in cervical smears and sections with remarkably high specificity and sensitivity.

Host Species: Mouse

Clone: DCS-180

Isotype: IgG1

Species Reactivity: Human. Others not known

Epitope: Not determined

Immunogen: Recombinant human CDC6 protein

Molecular Weight: 62 kDa

Positive Control: Raji or MDA231cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO