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Thermo Scientific™ Lab Vision™ CDC6 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ CDC6 Ab-1, Mouse Monoclonal Antibody.

$274.10 - $1,524.94

Specifications

Antigen CDC6 Ab-1
Clone DCS-180
Applications Immunoprecipitation,Western Blotting,Immunoprecipitation,Western Blotting
Classification Monoclonal
Format Concentrated
View More Specs


Products ${productFamilyLength}
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity  
Catalog Number Mfr. No. Concentration Conjugate Quantity Price Quantity  
MS867B Thermo Scientific™ Lab Vision™
MS867B
200μg/mL Biotin 1mL Each for $1,524.94
MS867B0 Thermo Scientific™ Lab Vision™
MS867B0
200μg/mL Biotin 100μL Each for $370.88
MS867B1 Thermo Scientific™ Lab Vision™
MS867B1
200μg/mL Biotin 500μL Each for $1,010.08
MS867P Thermo Scientific™ Lab Vision™
MS867P
200μg/mL Unlabeled 1mL Each for $1,180.18
MS867P0 Thermo Scientific™ Lab Vision™
MS867P0
200μg/mL Unlabeled 100μL Each for $274.10
MS867P1 Thermo Scientific™ Lab Vision™
MS867P1
200μg/mL Unlabeled 500μL Each for $776.88
MS867P1ABX Thermo Scientific™ Lab Vision™
MS867P1ABX
1mg/mL Unlabeled 100μL Each for $862.71
MS867PABX Thermo Scientific™ Lab Vision™
MS867PABX
1mg/mL Unlabeled 200μL Each for $1,283.73
Specifications

Description

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ CDC6 Ab-1, Mouse Monoclonal Antibody.

The replication licensing system acts to ensure that no section of the genome is replicated more than once in a single cell cycle. The origin recognition complex (ORC) and CDC6/CDC18 are needed on chromatin before the licensing reaction can take place. During the transition from a growth-arrested to a proliferative state, transcription of mammalian CDC6 is regulated by the cell cycle transcription factor (E2F protein). Immunoblots show that minichromosome maintenance (MCM) proteins are not associated with chromatin. Competence of G1 phase nuclei to replicate in vitro coincides with maximum CDC6 accumulation and MCM protein binding to chromatin in vivo. Antibodies against CDC6 and MCM5 stain abnormal (neoplastically transformed) cells in cervical smears and sections with remarkably high specificity and sensitivity.

Host Species: Mouse

Clone: DCS-180

Isotype: IgG1

Species Reactivity: Human. Others not known

Epitope: Not determined

Immunogen: Recombinant human CDC6 protein

Molecular Weight: 62 kDa

Positive Control: Raji or MDA231cells

Cellular Localization: Nuclear

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native and denatured)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

CDC6 Ab-1
Immunoprecipitation,Western Blotting,Immunoprecipitation,Western Blotting
Concentrated
RUO
Primary
IgG1
DCS-180
Monoclonal
Murine
Cell Cycle
Recombinant human CDC6 protein