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Thermo Scientific CDC25A Ab-1, Mouse Monoclonal Antibody


Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ CDC25A Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific  MS638P1ABX

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Catalog No. MS638P1ABX

  • / Each
 

Description & Specifications

Specifications

Antigen CDC25A Ab-1
Applications Immunoprecipitation
Classification Monoclonal
Clone DCS-120
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Rat
Format Purified
Host Species Mouse
Immunogen Purified recombinant CDC25A
Isotype IgG2a
Quantity 100µL
Regulatory Status RUO
Research Discipline Cell Cycle
Type Primary

Obtain accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ CDC25A Ab-1, Mouse Monoclonal Antibody.

Cyclin-dependent kinases are positively regulated by association with cyclins and negatively regulated by binding to inhibitory subunits. The activity of cyclin-dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of wee1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1-S-phase and G2 for CDC25B, CDC25C is predominantly expressed in G2.

Host Species: Mouse

Clone: DCS-120

Isotype: IgG2a

Species Reactivity: Human and Rat. Others not known.

Immunogen: Purified recombinant CDC25A

Molecular Weight: 65 kDa

Positive Control: LS174T cells, Tonsil

Cellular Localization: Nuclear membrane

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO