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CD93 (AA4.1) Rat anti-Mouse, PE, Clone: AA4.1, eBioscience™

Rat Monoclonal Antibody

$143.55 - $419.05

Specifications

Antigen CD93 (AA4.1)
Clone AA4.1
Host Species Rat
Gene Alias C1qRp, Early B lineage antigen
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010963

 
affymetrix
12-5892-81
50μg Each for $143.55

5010965

 
affymetrix
12589283
200μg Each for $419.05

501122342

 
affymetrix
12589282
100μg Each for $274.05
Description & Specifications

Specifications

Antigen CD93 (AA4.1)
Clone AA4.1
Host Species Rat
Gene Alias C1qRp, Early B lineage antigen
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The AA4.1 monoclonal antibody reacts with mouse C1qRp, an approximately 130-140kDa C-type lectin-like type I transmembrane protein. The AA4.1 antigen was originally identified as an antigen expressed on early stages of B cell development in bone marrow. Adult spleen and fetal liver also have detectable numbers of AA4.1 positive cells. In combination with other markers of hematopoietic progenitor cells such as Thy-1, Sca-1, c-Kit, CD43, and CD24, the bone marrow Lymphoid-Committed Progenitors (CLP) can be segregated into more primitive and more differentiated subsets based on expression of AA4.1. Correlated expression of surface IgM (sIgM), CD23, and AA4.1 antigen has also been used to define three nonproliferative subpopulations of immature/transitional peripheral B cells designated: T1 (AA4.1+/CD23-/sIgMhi), T2 (AA4.1+/CD23+/sIgMhi), and T3 (AA4.1+/CD23+/sIgMlo). AA4.1 is also reported to be expressed in cytoplasmic vesicles in endothelial cells, megakaryoblasts, and platelets. It is reported that monoclonal antibodies AA4.1 and 493 recognize different epitopes of the same molecule.