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CD91 Mouse anti-Human, eFluor 660, Clone: A2MR-a2, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $404.55

Specifications

Antigen CD91
Clone A2MR-a2
Host Species Mouse
Gene Alias LRP-1, Alpha-2-macroglobulin receptor
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124289

 
affymetrix
50091941
25 tests Each for $187.05

501124290

 
affymetrix
50091942
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen CD91
Clone A2MR-a2
Host Species Mouse
Gene Alias LRP-1, Alpha-2-macroglobulin receptor
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 660
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

The A2MR-a2 monoclonal antibody reacts with human CD91, also known as LRP-1 and alpha-2 macroglobulin receptor. CD91 is a 600 kDa, type 1 transmembrane protein consisting of an alpha and beta chain. The alpha chain interacts with multiple structurally and functionally diverse ligands and the beta chain contains 2 tyrosine phosphorylation motifs capable of interacting with adaptor and signaling proteins. Binding of ligands mediates ligand endocytosis and trafficking to lysosomes. This receptor is expressed by cells in the monocytic lineage, dendritic cells, hepatocytes, firbroblasts, adipocytes, neurons, and syncytiotrophoblast. CD91 is involved in cross-presenting antigens via MHC class I molecules on antigen presenting cells after endocytosis of heat shock protein-peptide complexes. It also plays a role in cell migration and is involved in activating signaling cascades.