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CD9 Rat anti-Mouse, Clone: eBioKMC8 (KMC8), eBioscience™

Rat Monoclonal Antibody

$85.55 - $361.05

Specifications

Antigen CD9
Clone eBioKMC8 (KMC8)
Host Species Rat
Gene Alias MIC3, Tspan29
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012400

 
affymetrix
14-0091-81
50μg Each for $85.55

5012401

 
affymetrix
14-0091-82
100μg Each for $158.05

5012402

 
affymetrix
14-0091-85
500μg Each for $361.05
Description & Specifications

Specifications

Antigen CD9
Clone eBioKMC8 (KMC8)
Host Species Rat
Gene Alias MIC3, Tspan29
Species Reactivity Mouse
Applications Flow Cytometry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioKMC8 monoclonal antibody reacts with mouse CD9, a 24kDa member of the transmembrane 4 superfamily. This family is characterized by the presence of four hydrophobic domains spanning the cell membrane and short N- and C-terminal cytoplasmic domains. CD9 is expressed by several cell types including monocytes, macrophages, platelets, early B cells, activated B and T cells, dendritic cells, eosinophils, basophils, endothelial cells, myoblasts and neuroblasts. On T cells, CD9 functions as a co-stimulatory molecule on naïve T cells. Furthermore, CD9 is expressed in oocytes, and CD9-deficiency results in sterility caused by defective gamete fusion. In mouse macrophages, CD9 functionally associates with FcγRs to modify signals for phagocytosis and inflammatory responses. In mouse B cells, it was discovered that CD9 is a marker for marginal zone B cells, B1 cells, and plasma cells. In dendritic cells, recently it was demonstrated that CD9 facilitates the association of heterologous MHC II molecules. The level of CD9 expression is subject to donor variability.