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CD8b Mouse anti-Rat, FITC, Clone: eBio341 (341), eBioscience™

Mouse Monoclonal Antibody

$129.05 - $375.55

Specifications

Antigen CD8b
Clone eBio341 (341)
Host Species Mouse
Gene Alias CD8 beta, Ly-3
Species Reactivity Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

509406

 
affymetrix
11-0080-81
50μg Each for $129.05

509407

 
affymetrix
11-0080-85
500μg Each for $375.55
Description & Specifications

Specifications

Antigen CD8b
Clone eBio341 (341)
Host Species Mouse
Gene Alias CD8 beta, Ly-3
Species Reactivity Rat
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBio341 monoclonal antibody reacts with rat CD8β. CD8β is a member of the immunoglobulin superfamily which heterodimerizes with CD8α to form the CD8 antigen expressed on CD4+CD8+, double-positive thymocytes, the majority of MHC class I-restricted peripheral T cells, and on some macrophages. CD8β expression is absent in athymic mice, which are populated by T-cells expressing CD8α homodimers. This has led to the idea that CD8β expression is dependent on the development of T cells in the thymus. CD8 binds to MHC class I expressed on the surface of antigen-presenting cells during antigen presentation, and participates in T-cell receptor signal transduction through association with the kinase Lck.