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CD8a Rat anti-Mouse, Clone: 53-6.7, Functional Grade, eBioscience™

Rat Monoclonal Antibody

$114.55 - $607.55

Specifications

Antigen CD8a
Clone 53-6.7
Host Species Rat
Gene Alias CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014212

 
affymetrix
16008181
50μg Each for $114.55

5014213

 
affymetrix
16008182
100μg Each for $172.55

5014214

 
affymetrix
16008185
500μg Each for $332.05

5014215

 
affymetrix
16008186
1mg Each for $607.55
Description & Specifications

Specifications

Antigen CD8a
Clone 53-6.7
Host Species Rat
Gene Alias CD8 alpha, Ly-2, Ly-35, Ly-B, Lyt-2
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide

The 53-6.7 monoclonal antibody reacts with the mouse CD8a molecule. CD8a is an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha beta) or as a homodimer (CD8 alpha alpha). A majority of thymocytes and a subpopulation of mature alpha beta TCR T cells express CD8 alpha beta while gamma delta TCR T cells, a subpopulation of intestinal intraepithelial lymphocytes (IELs) and dendritic cells express CD8 alpha alpha. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.